| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM25769 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_632382 (CHEMBL1115587) |
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| IC50 | 17±n/a nM |
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| Citation |  Baur, F; Beattie, D; Beer, D; Bentley, D; Bradley, M; Bruce, I; Charlton, SJ; Cuenoud, B; Ernst, R; Fairhurst, RA; Faller, B; Farr, D; Keller, T; Fozard, JR; Fullerton, J; Garman, S; Hatto, J; Hayden, C; He, H; Howes, C; Janus, D; Jiang, Z; Lewis, C; Loeuillet-Ritzler, F; Moser, H; Reilly, J; Steward, A; Sykes, D; Tedaldi, L; Trifilieff, A; Tweed, M; Watson, S; Wissler, E; Wyss, D The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist. J Med Chem53:3675-84 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_CAVPO | Adrb2 | adrenergic Beta2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46993.24 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 |
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| Residue: | 418 |
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| Sequence: | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
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| BDBM25769 |
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| n/a |
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| Name | BDBM25769 |
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| Synonyms: | 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol | Levalbuterol | Proventil | Salbutamol | Salbutamol,(+/-) | albuterol |
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| Type | Small organic molecule |
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| Emp. Form. | C13H21NO3 |
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| Mol. Mass. | 239.3107 |
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| SMILES | CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 |
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| Structure | 
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