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TargetAdenosine receptor A2b
LigandBDBM50331911
Substrate/Competitorn/a
Meas. Tech.ChEMBL_687329
Ki 1.7±n/a nM
Citation McGuinness BFHo KKStauffer TMRokosz LLMannava NKultgen SGSaionz KKlon AChen WDesai HRogers WLWebb MYin JJiang YLi TYan HJing KZhang SMajumdar KKSrivastava VSaha S Discovery of novel quinolinone adenosine A2B antagonists. Bioorg Med Chem Lett 20:7414-20 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A2b
Name:Adenosine receptor
Synonyms:ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36341.22
Organism:Homo sapiens (Human)
Description:n/a
Residue:332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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  Blast E-value cutoff:
BDBM50331911
n/a
NameBDBM50331911
Synonyms:(S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(1-phenylethyl)acetamide | CHEMBL1290210
TypeSmall organic molecule
Emp. Form.C30H27N3O3S
Mol. Mass.509.619
SMILESC[C@H](NC(=O)COc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1)c1ccccc1 |r|
Structure
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