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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | P2Y purinoceptor 14 | ||
| Ligand | BDBM50343122 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_745158 (CHEMBL1772337) | ||
| IC50 | 51±n/a nM | ||
| Citation |  Guay, D; Beaulieu, C; Belley, M; Crane, SN; DeLuca, J; Gareau, Y; Hamel, M; Henault, M; Hyjazie, H; Kargman, S; Chan, CC; Xu, L; Gordon, R; Li, L; Mamane, Y; Morin, N; Mancini, J; Thérien, M; Tranmer, G; Truong, VL; Wang, Z; Black, WC Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y14 receptor antagonists. Bioorg Med Chem Lett21:2832-5 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| P2Y purinoceptor 14 | |||
| Name: | P2Y purinoceptor 14 | ||
| Synonyms: | G-protein coupled receptor 105 | Gpr105 | P2Y14 | P2Y14_MOUSE | P2ry14 | UDP-glucose receptor | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 38883.93 | ||
| Organism: | Mus musculus | ||
| Description: | ChEMBL_745158 | ||
| Residue: | 338 | ||
| Sequence: |
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| BDBM50343122 | |||
| n/a | |||
| Name | BDBM50343122 | ||
| Synonyms: | 4-(2,6-dichlorophenyl)-N-(3-ethylphenyl)-2-(pyridin-3-yl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide | CHEMBL1771441 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H23Cl2N5O | ||
| Mol. Mass. | 504.41 | ||
| SMILES | CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2c(Cl)cccc2Cl)-c2cccnc2)c1 |(11.19,-15.22,;9.85,-14.45,;8.52,-15.23,;8.53,-16.78,;7.19,-17.55,;5.86,-16.78,;5.86,-15.24,;4.53,-14.47,;3.2,-15.24,;3.2,-16.78,;1.86,-14.47,;1.86,-12.92,;.52,-12.14,;-.82,-12.92,;-2.15,-12.16,;-3.48,-12.93,;-3.48,-14.48,;-2.15,-15.24,;-.82,-14.47,;.52,-15.24,;-2.14,-16.77,;-3.48,-17.54,;-4.81,-16.78,;-3.47,-19.08,;-2.14,-19.85,;-.8,-19.07,;-.81,-17.54,;.52,-16.76,;-4.81,-12.17,;-6.14,-12.94,;-7.48,-12.17,;-7.48,-10.62,;-6.15,-9.85,;-4.81,-10.62,;7.19,-14.47,)| | ||
| Structure | 
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