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Target1-deoxy-D-xylulose 5-phosphate reductoisomerase
LigandBDBM50153713
Substrate/Competitorn/a
Meas. Tech.ChEMBL_755773
Ki 140±n/a nM
Citation Deng LDiao JChen PPujari VYao YCheng GCrick DCPrasad BVSong Y Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies. J Med Chem 54:4721-34 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Name:1-deoxy-D-xylulose 5-phosphate reductoisomerase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:42846.92
Organism:Mycobacterium tuberculosis
Description:ChEMBL_1474510
Residue:413
Sequence:
MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQ
TGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTG
ARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGP
FRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVV
VHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEP
LDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQ
WAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS
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  Blast E-value cutoff:
BDBM50153713
n/a
NameBDBM50153713
Synonyms:3-(N-hydroxyformamido)propylphosphonic acid | 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID | CHEMBL203125 | [3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid | fosmidomycin
TypeSmall organic molecule
Emp. Form.C4H10NO5P
Mol. Mass.183.0997
SMILESON(CCCP(O)(O)=O)C=O
Structure
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