Reaction Details | |||
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Target | Neuropeptide Y receptor type 5 | ||
Ligand | BDBM50353151 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_768586 (CHEMBL1832605) | ||
Ki | 0.6±n/a nM | ||
Citation | Wu, L; Lu, K; Desai, M; Packiarajan, M; Joshi, A; Marzabadi, MR; Jubian, V; Andersen, K; Chandrasena, G; Boyle, NJ; Walker, MW N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists. Bioorg Med Chem Lett21:5573-6 (2011) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neuropeptide Y receptor type 5 | |||
Name: | Neuropeptide Y receptor type 5 | ||
Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
Type: | Enzyme | ||
Mol. Mass.: | 50746.64 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q15761 | ||
Residue: | 445 | ||
Sequence: |
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BDBM50353151 | |||
n/a | |||
Name | BDBM50353151 | ||
Synonyms: | CHEMBL1829323 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H30ClN3O3S2 | ||
Mol. Mass. | 460.054 | ||
SMILES | CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NC(=O)CN1CCSc2cc(Cl)ccc12 |r,wU:11.14,wD:8.7,(10.22,-17.24,;8.89,-16.47,;8.89,-14.93,;7.56,-17.23,;6.77,-18.56,;8.31,-18.56,;6.22,-16.46,;4.89,-17.23,;3.56,-16.46,;3.56,-14.92,;2.22,-14.14,;.89,-14.92,;.89,-16.46,;2.22,-17.22,;-.45,-14.14,;-1.77,-14.92,;-1.77,-16.46,;-3.11,-14.15,;-4.44,-14.92,;-4.44,-16.47,;-5.78,-17.23,;-7.11,-16.46,;-7.11,-14.93,;-8.45,-14.16,;-8.45,-12.62,;-9.78,-11.85,;-7.12,-11.85,;-5.78,-12.61,;-5.77,-14.16,)| | ||
Structure |