Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50353157 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_768586 (CHEMBL1832605) | ||
| Ki | 88±n/a nM | ||
| Citation |  Wu, L; Lu, K; Desai, M; Packiarajan, M; Joshi, A; Marzabadi, MR; Jubian, V; Andersen, K; Chandrasena, G; Boyle, NJ; Walker, MW N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists. Bioorg Med Chem Lett21:5573-6 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
| ||
| BDBM50353157 | |||
| n/a | |||
| Name | BDBM50353157 | ||
| Synonyms: | CHEMBL1829329 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H35N3O4S | ||
| Mol. Mass. | 425.585 | ||
| SMILES | COc1ccc2N(CCN[C@H]3CC[C@H](CNS(=O)(=O)C(C)C)CC3)CCOc2c1 |r,wU:13.13,wD:10.9,(-9.34,-36.38,;-9.34,-37.92,;-8.01,-38.7,;-6.68,-37.92,;-5.34,-38.69,;-5.34,-40.24,;-4,-41,;-2.67,-40.23,;-1.34,-40.99,;-.01,-40.22,;1.32,-40.99,;1.32,-42.53,;2.65,-43.3,;3.99,-42.53,;5.32,-43.31,;6.65,-42.53,;7.98,-43.31,;7.2,-44.64,;8.74,-44.64,;9.31,-42.54,;10.64,-43.32,;9.32,-41,;3.99,-40.99,;2.65,-40.22,;-4.01,-42.54,;-5.34,-43.31,;-6.67,-42.53,;-6.67,-41,;-8.01,-40.24,)| | ||
| Structure | 
| ||