Reaction Details | |||
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Target | Neuropeptide Y receptor type 5 | ||
Ligand | BDBM50353159 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_768586 (CHEMBL1832605) | ||
Ki | 14±n/a nM | ||
Citation | Wu, L; Lu, K; Desai, M; Packiarajan, M; Joshi, A; Marzabadi, MR; Jubian, V; Andersen, K; Chandrasena, G; Boyle, NJ; Walker, MW N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists. Bioorg Med Chem Lett21:5573-6 (2011) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neuropeptide Y receptor type 5 | |||
Name: | Neuropeptide Y receptor type 5 | ||
Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
Type: | Enzyme | ||
Mol. Mass.: | 50746.64 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q15761 | ||
Residue: | 445 | ||
Sequence: |
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BDBM50353159 | |||
n/a | |||
Name | BDBM50353159 | ||
Synonyms: | CHEMBL1829331 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H32ClN3O3S | ||
Mol. Mass. | 430.004 | ||
SMILES | CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NCCN1CCOc2cc(Cl)ccc12 |r,wU:8.7,wD:11.14,(10.45,-.43,;9.12,.34,;9.12,1.88,;7.78,-.43,;7,-1.75,;8.54,-1.75,;6.45,.35,;5.11,-.42,;3.78,.35,;2.45,-.41,;1.12,.36,;1.12,1.9,;2.45,2.67,;3.78,1.9,;-.21,2.66,;-1.55,1.89,;-2.88,2.66,;-4.21,1.89,;-4.22,.35,;-5.55,-.42,;-6.88,.35,;-6.88,1.88,;-8.22,2.65,;-8.22,4.19,;-9.55,4.96,;-6.89,4.96,;-5.55,4.2,;-5.55,2.65,)| | ||
Structure |