| Reaction Details |
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 | Report a problem with these data |
| Target | Protein tyrosine phosphatase type IVA 3 |
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| Ligand | BDBM11318 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_795371 (CHEMBL1937271) |
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| IC50 | 3500±n/a nM |
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| Citation |  Han, YM; Lee, SK; Jeong, DG; Ryu, SE; Han, DC; Kim, DK; Kwon, BM Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity. Bioorg Med Chem Lett22:323-6 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein tyrosine phosphatase type IVA 3 |
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| Name: | Protein tyrosine phosphatase type IVA 3 |
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| Synonyms: | PRL3 | PTP4A3 | Protein-tyrosine phosphatase 4A3 | TP4A3_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 19546.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1461022 |
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| Residue: | 173 |
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| Sequence: | MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
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| BDBM11318 |
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| n/a |
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| Name | BDBM11318 |
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| Synonyms: | 1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9,10-dione | 1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHEMBL289277 | Emodin | US20230364057, Compound 242 | med.21724, Compound 24 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10O5 |
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| Mol. Mass. | 270.2369 |
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| SMILES | Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 |
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| Structure | 
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