| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50363833 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_802200 (CHEMBL1949358) |
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| Kd | 3.16±n/a nM |
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| Citation |  Wang, JL; Zhang, J; Zhou, ZM; Li, ZH; Xue, WZ; Xu, D; Hao, LP; Han, XF; Fei, F; Liu, T; Liang, AH Design, synthesis and biological evaluation of 6-substituted aminocarbonyl benzimidazole derivatives as nonpeptidic angiotensin II AT1 receptor antagonists. Eur J Med Chem49:183-90 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41009.15 |
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| Organism: | RABBIT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RABBIT::P34976 |
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| Residue: | 359 |
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| Sequence: | MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
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| BDBM50363833 |
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| n/a |
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| Name | BDBM50363833 |
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| Synonyms: | CHEMBL1945010 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H37N3O5 |
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| Mol. Mass. | 591.6961 |
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| SMILES | CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NCCc1cc(OC)ccc1OC |
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| Structure | 
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