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TargetTissue alpha-L-fucosidase
LigandBDBM50065259
Substrate/Competitorn/a
Meas. Tech.ChEMBL_33966 (CHEMBL649591)
Ki 4700±n/a nM
Citation Asano, N; Nishida, M; Kato, A; Kizu, H; Matsui, K; Shimada, Y; Itoh, T; Baba, M; Watson, AA; Nash, RJ; Lilley, PM; Watkin, DJ; Fleet, GW Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. J Med Chem41:2565-71 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Tissue alpha-L-fucosidase
Name:Tissue alpha-L-fucosidase
Synonyms:Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:PROTEIN
Mol. Mass.:53690.69
Organism:Homo sapiens (Human)
Description:ChEMBL_34088
Residue:466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGV
FIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEW
ADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYG
LYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYW
NSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSID
KFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGK
WLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTK
ITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
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  Blast E-value cutoff:
BDBM50065259
n/a
NameBDBM50065259
Synonyms:(2R,3R,4R,5R)-2-(Hydroxymethyl)piperidine-3,4,5-triol, 11 | (2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol | (2R,3R,4R,5R)-2-Hydroxymethyl-piperidine-3,4,5-triol | 1-DEOXYMANNOJIRIMYCIN | 2-HYDROXYMETHYL-PIPERIDINE-3,4,5-TRIOL | CHEMBL84844 | deoxymannojirimycin
TypeSmall organic molecule
Emp. Form.C6H13NO4
Mol. Mass.163.1717
SMILESOC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O |r|
Structure
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