| Reaction Details |
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 | Report a problem with these data |
| Target | Tissue alpha-L-fucosidase |
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| Ligand | BDBM50408432 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34094 (CHEMBL649723) |
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| IC50 | 4400±n/a nM |
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| Citation |  Asano, N; Nishida, M; Kato, A; Kizu, H; Matsui, K; Shimada, Y; Itoh, T; Baba, M; Watson, AA; Nash, RJ; Lilley, PM; Watkin, DJ; Fleet, GW Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases. J Med Chem41:2565-71 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tissue alpha-L-fucosidase |
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| Name: | Tissue alpha-L-fucosidase |
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| Synonyms: | Alpha-L-fucosidase I | FUCO_RAT | Fuca | Fuca1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53482.81 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_990950 |
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| Residue: | 462 |
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| Sequence: | MWDLKSEWWAVGFGLLLLLAASAQAGGLAPHHYTPDWPSLDSRPLPRWFDEAKFGLFVHW
GVYSVPAWGSEWFWWHWQGEQSSAYVRFMKENYPPGFSYADFAPQFTARFFHPEEWADLF
QAAGAKYVVLTAKHHEGFTNWPSAVSWNWNSKDVGPHRDLVGELGAAVRKRNIRYGLYHS
LFEWFHPLYLLDKKNGLKTQHFVSTKTMPELYDLVNRYKPDLIWSDGEWECPDSYWNSTE
FLAWLYNESPVKDQVVVNDRWGQNCSCRHGGYYNCEDKYRPHSLPDHKWEMCTSVDKASW
GYRRDMSMSTIVDENEIIEELVQTISLGGNYLLNIGPNKDGVIVPIFQERLLAVGKWLQI
NGEAIYASKPWRVQSERNKTVVWYTTKDSAVYATFLHWPEDGVVNLQSPKMTSATKITML
GMEGELHWTQDPLEGVLITLPQLPPGTFPVESAWTLKLTKVN
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| BDBM50408432 |
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| n/a |
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| Name | BDBM50408432 |
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| Synonyms: | CHEMBL2115215 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H15NO5 |
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| Mol. Mass. | 193.1977 |
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| SMILES | OC[C@H]1N[C@@H](CO)[C@@H](O)[C@@H](O)[C@@H]1O |
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| Structure | 
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