Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50291973 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_145155 (CHEMBL755959) |
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Ki | 421±n/a nM |
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Citation | Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Identification of an opioid kappa receptor subtype-selective N-substituent for (+)-(3R,4R)-dimethyl-4-(3-hydroxyphenyl)piperidine. J Med Chem41:5188-97 (1999) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 11165.58 |
Organism: | GUINEA PIG |
Description: | P97266 |
Residue: | 98 |
Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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BDBM50291973 |
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n/a |
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Name | BDBM50291973 |
Synonyms: | 3-(4-Hydroxy-phenyl)-N-{(S)-1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-butyl}-propionamide | CHEMBL151243 |
Type | Small organic molecule |
Emp. Form. | C28H40N2O3 |
Mol. Mass. | 452.6288 |
SMILES | CCC(C)[C@@H](CN1CCC(C)(C(C)C1)c1cccc(O)c1)NC(=O)CCc1ccc(O)cc1 |
Structure |
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