| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50085049 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_148528 (CHEMBL755189) |
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| Ki | 218±n/a nM |
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| Citation |  Schiller, PW; Berezowska, I; Nguyen, TM; Schmidt, R; Lemieux, C; Chung, NN; Falcone-Hindley, ML; Yao, W; Liu, J; Iwama, S; Smith, AB; Hirschmann, R Novel ligands lacking a positive charge for the delta- and mu-opioid receptors. J Med Chem43:551-9 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50085049 |
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| n/a |
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| Name | BDBM50085049 |
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| Synonyms: | CHEMBL152689 | CHO-Dmt-c [-D-Orn-2-Nal-D-Pro-Gly-] |
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| Type | Small organic molecule |
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| Emp. Form. | C37H44N6O7 |
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| Mol. Mass. | 684.7813 |
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| SMILES | Cc1cc(O)cc(C)c1C[C@H](NC=O)C(=O)N[C@@H]1CCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O |
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| Structure | 
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