| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50086880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_160747 (CHEMBL769061) |
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| Ki | 1±n/a nM |
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| Citation |  Fairlie, DP; Tyndall, JD; Reid, RC; Wong, AK; Abbenante, G; Scanlon, MJ; March, DR; Bergman, DA; Chai, CL; Burkett, BA Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing. J Med Chem43:1271-81 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
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| BDBM50086880 |
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| n/a |
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| Name | BDBM50086880 |
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| Synonyms: | Proteolytic Enzyme inhibitor |
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| Type | Small organic molecule |
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| Emp. Form. | C45H71N10O16S |
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| Mol. Mass. | 1040.168 |
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| SMILES | CC(C)C[C@@H](NC(=O)[C@H](O)COS([O-])(=O)=O)C(=O)N[C@H]1[C@@H](C)OC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)N(C)C(=O)[C@H](CC(C)C)N2[C@@H](O)CC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC1=O)C2=O)C(C)C |
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| Structure | 
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