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TargetMethionine aminopeptidase
LigandBDBM50129640
Substrate/Competitorn/a
Meas. Tech.ChEMBL_105132 (CHEMBL872687)
IC50 220±n/a nM
Citation Luo, QLLi, JYLiu, ZYChen, LLLi, JQian, ZShen, QLi, YLushington, GHYe, QZNan, FJ Discovery and structural modification of inhibitors of methionine aminopeptidases from Escherichia coli and Saccharomyces cerevisiae. J Med Chem46:2631-40 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Methionine aminopeptidase
Name:Methionine aminopeptidase
Synonyms:EcMetAP | MAP1_ECOLI | Methionine Aminopeptidase (MAP) | Methionine aminopeptidase | Peptidase M | map
Type:Enzyme
Mol. Mass.:29326.96
Organism:Escherichia coli (strain K12)
Description:Full-length untagged EcMAP was expressed in E. coli.
Residue:264
Sequence:
MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACL
GYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTI
MGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEE
PQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVV
TDNGCEILTLRKDDTIPAIISHDE
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  Blast E-value cutoff:
BDBM50129640
n/a
NameBDBM50129640
Synonyms:3-(3-Methyl-but-2-enoylamino)-pyridine-2-carboxylic acid thiazol-2-ylamide | CHEMBL313629
TypeSmall organic molecule
Emp. Form.C14H14N4O2S
Mol. Mass.302.352
SMILES[#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Structure
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