| Reaction Details |
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 | Report a problem with these data |
| Target | Motilin receptor |
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| Ligand | BDBM50143029 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_122661 (CHEMBL732791) |
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| EC50 | >10000±n/a nM |
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| Citation |  Li, JJ; Chao, HG; Wang, H; Tino, JA; Lawrence, RM; Ewing, WR; Ma, Z; Yan, M; Slusarchyk, D; Seethala, R; Sun, H; Li, D; Burford, NT; Stoffel, RH; Salyan, ME; Li, CY; Witkus, M; Zhao, N; Rich, A; Gordon, DA Discovery of a potent and novel motilin agonist. J Med Chem47:1704-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Motilin receptor |
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| Name: | Motilin receptor |
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| Synonyms: | G-protein coupled receptor 38 | GPR38 | MLNR | MTLR | MTLR1 | MTLR_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45365.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_122664 |
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| Residue: | 412 |
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| Sequence: | MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
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| BDBM50143029 |
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| n/a |
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| Name | BDBM50143029 |
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| Synonyms: | 8'N-[1-carbamoyl-(1S)-ethyl]-2'-benzo[d][1,3]dioxol-5-ylmethyl-1',3'-dioxospiro[hexahydropyridine-4,5'-(2',3',5',8'-tetrahydro-1'H-[1,2,4]triazolo[1,2-a]pyridazine)]-8'-carboxamide | CHEMBL296962 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N6O6 |
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| Mol. Mass. | 470.4784 |
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| SMILES | C[C@H](NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O)C(N)=O |c:6| |
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| Structure | 
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