Compile Data Set for Download or QSAR

Found 57 hits with Last Name = 'salyan' and Initial = 'me'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Motilin receptor (Homo sapiens (Human))	BDBM50143028 (8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...) Show SMILES NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)C1CCC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O Show InChI InChI=1S/C39H45N7O7/c40-34(47)29(14-11-26-7-3-1-4-8-26)42-35(48)30(15-12-27-9-5-2-6-10-27)43-36(49)31-17-18-39(19-21-41-22-20-39)46-38(51)44(37(50)45(31)46)24-28-13-16-32-33(23-28)53-25-52-32/h1-10,13,16,23,29-31,41H,11-12,14-15,17-22,24-25H2,(H2,40,47)(H,42,48)(H,43,49)/t29-,30-,31?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143032 (8'N-[1-(1-carbamoyl-3-phenylpropylcarbamoyl)-3-phe...) Show SMILES NC(=O)C(CCc1ccccc1)NC(=O)C(CCc1ccccc1)NC(=O)C1CCC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O Show InChI InChI=1S/C39H45N7O7/c40-34(47)29(14-11-26-7-3-1-4-8-26)42-35(48)30(15-12-27-9-5-2-6-10-27)43-36(49)31-17-18-39(19-21-41-22-20-39)46-38(51)44(37(50)45(31)46)24-28-13-16-32-33(23-28)53-25-52-32/h1-10,13,16,23,29-31,41H,11-12,14-15,17-22,24-25H2,(H2,40,47)(H,42,48)(H,43,49)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143038 (8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...) Show SMILES NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:30| Show InChI InChI=1S/C39H43N7O7/c40-34(47)29(14-11-26-7-3-1-4-8-26)42-35(48)30(15-12-27-9-5-2-6-10-27)43-36(49)31-17-18-39(19-21-41-22-20-39)46-38(51)44(37(50)45(31)46)24-28-13-16-32-33(23-28)53-25-52-32/h1-10,13,16-18,23,29-31,41H,11-12,14-15,19-22,24-25H2,(H2,40,47)(H,42,48)(H,43,49)/t29-,30-,31?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143039 (8'N-[1-[1-carbamoyl-3-phenyl-(1R)-propylcarbamoyl]...) Show SMILES NC(=O)[C@@H](CCc1ccccc1)NC(=O)[C@@H](CCc1ccccc1)NC(=O)C1CCC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O Show InChI InChI=1S/C39H45N7O7/c40-34(47)29(14-11-26-7-3-1-4-8-26)42-35(48)30(15-12-27-9-5-2-6-10-27)43-36(49)31-17-18-39(19-21-41-22-20-39)46-38(51)44(37(50)45(31)46)24-28-13-16-32-33(23-28)53-25-52-32/h1-10,13,16,23,29-31,41H,11-12,14-15,17-22,24-25H2,(H2,40,47)(H,42,48)(H,43,49)/t29-,30-,31?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143037 (CHEMBL411576 | MOTILIN) Show SMILES CCC(C)C(NC(=O)C1CCCN1C(=O)C(NC(=O)C(N)Cc1ccccc1)C(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCSC)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(O)=O)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(N)=O)C(O)=O Show InChI InChI=1S/C120H188N34O35S/c1-9-64(6)97(152-114(184)86-31-22-53-154(86)117(187)96(63(4)5)151-99(169)70(123)56-66-23-12-10-13-24-66)115(185)150-84(57-67-25-14-11-15-26-67)113(183)153-98(65(7)155)116(186)149-83(58-68-32-34-69(156)35-33-68)101(171)135-60-91(161)136-75(39-45-93(163)164)105(175)147-82(55-62(2)3)111(181)145-77(37-43-88(125)158)106(176)140-73(29-20-51-132-119(128)129)103(173)146-80(48-54-190-8)110(180)142-76(36-42-87(124)157)107(177)144-79(41-47-95(167)168)108(178)139-72(28-17-19-50-122)102(172)143-78(40-46-94(165)166)109(179)141-74(30-21-52-133-120(130)131)104(174)148-85(59-90(127)160)112(182)138-71(27-16-18-49-121)100(170)134-61-92(162)137-81(118(188)189)38-44-89(126)159/h10-15,23-26,32-35,62-65,70-86,96-98,155-156H,9,16-22,27-31,36-61,121-123H2,1-8H3,(H2,124,157)(H2,125,158)(H2,126,159)(H2,127,160)(H,134,170)(H,135,171)(H,136,161)(H,137,162)(H,138,182)(H,139,178)(H,140,176)(H,141,179)(H,142,180)(H,143,172)(H,144,177)(H,145,181)(H,146,173)(H,147,175)(H,148,174)(H,149,186)(H,150,185)(H,151,169)(H,152,184)(H,153,183)(H,163,164)(H,165,166)(H,167,168)(H,188,189)(H4,128,129,132)(H4,130,131,133)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50344952 ((2R,3S,4R,5R,8R,9S,10S,11R,12S)-5-ethyl-11-((2S,3R...) Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@](C)(C[C@@H](C)O2)OC)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)CC)[C@@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@H]1C |wU:24.24,8.8,29.33,36.38,6.6,20.21,2.1,12.12,26.27,wD:22.23,10.9,30.32,45.48,12.18,43.46,47.51,15.15,c:42,(6.35,-6.68,;6.37,-5.14,;7.71,-4.39,;7.7,-5.93,;9.03,-6.7,;9.01,-8.24,;10.37,-5.93,;11.7,-6.7,;10.37,-4.39,;11.7,-5.16,;13.03,-5.93,;13.03,-7.47,;14.35,-8.24,;13.56,-9.57,;15.69,-7.47,;15.69,-5.95,;17.02,-5.16,;14.36,-5.16,;15.1,-9.57,;16.64,-9.57,;11.71,-3.64,;13.04,-4.42,;11.72,-2.1,;13.05,-1.34,;14.38,-.56,;15.71,-1.31,;17.04,-.56,;18.37,-1.33,;17.04,.98,;15.71,1.77,;14.38,.98,;13.05,1.75,;15.71,3.31,;17.04,4.08,;14.38,4.08,;14.38,5.62,;10.39,-1.31,;11.72,-.54,;10.39,.23,;9.06,1,;9.08,2.54,;7.73,.23,;8.82,-.85,;7.72,-1.31,;6.38,-.54,;6.39,-2.08,;5.06,-1.29,;6.38,-3.62,;5.04,-4.35,)| Show InChI InChI=1S/C38H67NO10/c1-14-28-23(6)30(40)24(7)32-20(3)17-38(11,49-32)34(48-36-31(41)27(39(12)15-2)16-21(4)45-36)25(8)33(26(9)35(42)46-28)47-29-19-37(10,43-13)18-22(5)44-29/h21-31,33-34,36,40-41H,14-19H2,1-13H3/t21-,22-,23+,24-,25+,26-,27+,28-,29+,30+,31-,33+,34-,36+,37+,38-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143034 (8'N-[1-carbamoyl-3-phenyl-(1S)-propyl]-2'-benzo[d]...) Show SMILES NC(=O)[C@H](CCc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:17| Show InChI InChI=1S/C29H32N6O6/c30-25(36)21(8-6-19-4-2-1-3-5-19)32-26(37)22-10-11-29(12-14-31-15-13-29)35-28(39)33(27(38)34(22)35)17-20-7-9-23-24(16-20)41-18-40-23/h1-5,7,9-11,16,21-22,31H,6,8,12-15,17-18H2,(H2,30,36)(H,32,37)/t21-,22?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143033 (CHEMBL46272 | methyl 2-[2'-benzo[d][1,3]dioxol-5-y...) Show SMILES COC(=O)[C@@H](CCc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:18| Show InChI InChI=1S/C30H33N5O7/c1-40-27(37)22(9-7-20-5-3-2-4-6-20)32-26(36)23-11-12-30(13-15-31-16-14-30)35-29(39)33(28(38)34(23)35)18-21-8-10-24-25(17-21)42-19-41-24/h2-6,8,10-12,17,22-23,31H,7,9,13-16,18-19H2,1H3,(H,32,36)/t22-,23?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143031 (8'N-[1-carbamoyl-3-phenyl-(1R)-propyl]-2'-benzo[d]...) Show SMILES NC(=O)[C@@H](CCc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:17| Show InChI InChI=1S/C29H32N6O6/c30-25(36)21(8-6-19-4-2-1-3-5-19)32-26(37)22-10-11-29(12-14-31-15-13-29)35-28(39)33(27(38)34(22)35)17-20-7-9-23-24(16-20)41-18-40-23/h1-5,7,9-11,16,21-22,31H,6,8,12-15,17-18H2,(H2,30,36)(H,32,37)/t21-,22?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143034 (8'N-[1-carbamoyl-3-phenyl-(1S)-propyl]-2'-benzo[d]...) Show SMILES NC(=O)[C@H](CCc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:17| Show InChI InChI=1S/C29H32N6O6/c30-25(36)21(8-6-19-4-2-1-3-5-19)32-26(37)22-10-11-29(12-14-31-15-13-29)35-28(39)33(27(38)34(22)35)17-20-7-9-23-24(16-20)41-18-40-23/h1-5,7,9-11,16,21-22,31H,6,8,12-15,17-18H2,(H2,30,36)(H,32,37)/t21-,22?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50344942 (CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCI...) Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O |r| Show InChI InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair				3D Structure (crystal)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32522 (pyridine amide, 30) Show SMILES Cc1ccc(cc1F)-c1cccc(n1)C(=O)N1CCCC(C)(C)C1 Show InChI InChI=1S/C20H23FN2O/c1-14-8-9-15(12-16(14)21)17-6-4-7-18(22-17)19(24)23-11-5-10-20(2,3)13-23/h4,6-9,12H,5,10-11,13H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (crystal)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32521 (pyridine amide, 29) Show SMILES CC1(C)CCCN(C1)C(=O)c1cccc(n1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C20H21F3N2O2/c1-19(2)11-4-12-25(13-19)18(26)17-6-3-5-16(24-17)14-7-9-15(10-8-14)27-20(21,22)23/h3,5-10H,4,11-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32520 (pyridine amide, 28) Show SMILES CC1(C)CCCN(C1)C(=O)c1cccc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O/c1-19(2)11-4-12-22(13-19)18(23)17-6-3-5-16(21-17)14-7-9-15(20)10-8-14/h3,5-10H,4,11-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32527 (pyridine amide, 35) Show SMILES [H][C@]12C[C@](C)(CN1C(=O)c1cncc(COc3c(Cl)cccc3Cl)c1)CC(C)(C)C2 |r| Show InChI InChI=1S/C23H26Cl2N2O2/c1-22(2)8-17-9-23(3,13-22)14-27(17)21(28)16-7-15(10-26-11-16)12-29-20-18(24)5-4-6-19(20)25/h4-7,10-11,17H,8-9,12-14H2,1-3H3/t17-,23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32523 (pyridine amide, 31) Show SMILES [O-][N+](=O)c1ccccc1-c1cccc(n1)C(=O)N1CCCC2CCCCC12 Show InChI InChI=1S/C21H23N3O3/c25-21(23-14-6-8-15-7-1-3-12-19(15)23)18-11-5-10-17(22-18)16-9-2-4-13-20(16)24(26)27/h2,4-5,9-11,13,15,19H,1,3,6-8,12,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32526 (pyridine amide, 34) Show SMILES Clc1cccc(Cl)c1OCc1cncc(c1)C(=O)N1CCCCC1c1cccnc1 Show InChI InChI=1S/C23H21Cl2N3O2/c24-19-6-3-7-20(25)22(19)30-15-16-11-18(14-27-12-16)23(29)28-10-2-1-8-21(28)17-5-4-9-26-13-17/h3-7,9,11-14,21H,1-2,8,10,15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32508 (pyridine amide, 23) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCCCCCCC1 Show InChI InChI=1S/C21H24Cl2N2O3S/c22-18-8-7-9-19(23)20(18)29(27,28)15-16-12-17(14-24-13-16)21(26)25-10-5-3-1-2-4-6-11-25/h7-9,12-14H,1-6,10-11,15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32519 (pyridine amide, 27) Show SMILES CC1(C)CCCN(C1)C(=O)c1cccc(n1)-c1ccccc1Cl Show InChI InChI=1S/C19H21ClN2O/c1-19(2)11-6-12-22(13-19)18(23)17-10-5-9-16(21-17)14-7-3-4-8-15(14)20/h3-5,7-10H,6,11-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32524 (pyridine amide, 32) Show SMILES FC(F)(F)c1ccc(cc1)-c1cccc(n1)C(=O)N1CCCC2CCCCC12 Show InChI InChI=1S/C22H23F3N2O/c23-22(24,25)17-12-10-15(11-13-17)18-7-3-8-19(26-18)21(28)27-14-4-6-16-5-1-2-9-20(16)27/h3,7-8,10-13,16,20H,1-2,4-6,9,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32529 (pyridine amide, 37) Show SMILES Clc1cccc(Cl)c1OCc1cccc(n1)C(=O)N1CCCC2CCCCC12 Show InChI InChI=1S/C22H24Cl2N2O2/c23-17-9-4-10-18(24)21(17)28-14-16-8-3-11-19(25-16)22(27)26-13-5-7-15-6-1-2-12-20(15)26/h3-4,8-11,15,20H,1-2,5-7,12-14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32525 (pyridine amide, 33) Show SMILES O=C(N1CCCC2CCCCC12)c1cccc(n1)-c1ccccc1-c1ccccc1 Show InChI InChI=1S/C27H28N2O/c30-27(29-19-9-13-21-12-4-7-18-26(21)29)25-17-8-16-24(28-25)23-15-6-5-14-22(23)20-10-2-1-3-11-20/h1-3,5-6,8,10-11,14-17,21,26H,4,7,9,12-13,18-19H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32528 (pyridine amide, 36) Show SMILES CC1(C)CCCN(C1)C(=O)c1cccc(COc2c(Cl)cc(Cl)cc2Cl)n1 Show InChI InChI=1S/C20H21Cl3N2O2/c1-20(2)7-4-8-25(12-20)19(26)17-6-3-5-14(24-17)11-27-18-15(22)9-13(21)10-16(18)23/h3,5-6,9-10H,4,7-8,11-12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32512 (pyridine amide, 6) Show SMILES CC1CCN(CC1)C(=O)c1cccc(CSc2c(Cl)cccc2Cl)n1 Show InChI InChI=1S/C19H20Cl2N2OS/c1-13-8-10-23(11-9-13)19(24)17-7-2-4-14(22-17)12-25-18-15(20)5-3-6-16(18)21/h2-7,13H,8-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32507 (pyridine amide, 22) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCCCCCC1 Show InChI InChI=1S/C20H22Cl2N2O3S/c21-17-7-6-8-18(22)19(17)28(26,27)14-15-11-16(13-23-12-15)20(25)24-9-4-2-1-3-5-10-24/h6-8,11-13H,1-5,9-10,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32518 (pyridine amide, 9) Show SMILES CC1CCN(CC1)C(=O)c1cccc(n1)-c1ccccc1Cl Show InChI InChI=1S/C18H19ClN2O/c1-13-9-11-21(12-10-13)18(22)17-8-4-7-16(20-17)14-5-2-3-6-15(14)19/h2-8,13H,9-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair				3D Structure (docked)
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32506 (pyridine amide, 21) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCCCCC1 Show InChI InChI=1S/C19H20Cl2N2O3S/c20-16-6-5-7-17(21)18(16)27(25,26)13-14-10-15(12-22-11-14)19(24)23-8-3-1-2-4-9-23/h5-7,10-12H,1-4,8-9,13H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32500 (pyridine amide, 15) Show SMILES CC1CCN(CC1)C(=O)c1cncc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1 Show InChI InChI=1S/C19H20Cl2N2O3S/c1-13-5-7-23(8-6-13)19(24)15-9-14(10-22-11-15)12-27(25,26)18-16(20)3-2-4-17(18)21/h2-4,9-11,13H,5-8,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32499 (pyridine amide, 8) Show SMILES CC1CCN(CC1)C(=O)c1cccc(CS(=O)(=O)c2c(Cl)cccc2Cl)n1 Show InChI InChI=1S/C19H20Cl2N2O3S/c1-13-8-10-23(11-9-13)19(24)17-7-2-4-14(22-17)12-27(25,26)18-15(20)5-3-6-16(18)21/h2-7,13H,8-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32513 (pyridine amide, 7) Show SMILES CC1CCN(CC1)C(=O)c1cccc(COc2c(Cl)cccc2Cl)n1 Show InChI InChI=1S/C19H20Cl2N2O2/c1-13-8-10-23(11-9-13)19(24)17-7-2-4-14(22-17)12-25-18-15(20)5-3-6-16(18)21/h2-7,13H,8-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32501 (pyridine amide, 16) Show SMILES CC1CCN(CC1)C(=O)c1ccnc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1 Show InChI InChI=1S/C19H20Cl2N2O3S/c1-13-6-9-23(10-7-13)19(24)14-5-8-22-15(11-14)12-27(25,26)18-16(20)3-2-4-17(18)21/h2-5,8,11,13H,6-7,9-10,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32514 (pyridine amide, 11) Show SMILES CC1CCN(CC1)C(=O)c1cccc(Sc2ccccc2Cl)n1 Show InChI InChI=1S/C18H19ClN2OS/c1-13-9-11-21(12-10-13)18(22)15-6-4-8-17(20-15)23-16-7-3-2-5-14(16)19/h2-8,13H,9-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	218	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32509 (pyridine amide, 24) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCCCC1 Show InChI InChI=1S/C18H18Cl2N2O3S/c19-15-5-4-6-16(20)17(15)26(24,25)12-13-9-14(11-21-10-13)18(23)22-7-2-1-3-8-22/h4-6,9-11H,1-3,7-8,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32515 (pyridine amide, 12) Show SMILES CC1CCN(CC1)C(=O)c1cccc(Oc2ccccc2Cl)n1 Show InChI InChI=1S/C18H19ClN2O2/c1-13-9-11-21(12-10-13)18(22)15-6-4-8-17(20-15)23-16-7-3-2-5-14(16)19/h2-8,13H,9-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	282	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32502 (pyridine amide, 17) Show SMILES CC1CCN(CC1)C(=O)c1cc(CS(=O)(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C19H20Cl2N2O3S/c1-13-6-9-23(10-7-13)19(24)17-11-14(5-8-22-17)12-27(25,26)18-15(20)3-2-4-16(18)21/h2-5,8,11,13H,6-7,9-10,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	319	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32516 (pyridine amide, 13) Show SMILES CC1CCN(CC1)C(=O)c1cccc(Nc2ccccc2Cl)n1 Show InChI InChI=1S/C18H20ClN3O/c1-13-9-11-22(12-10-13)18(23)16-7-4-8-17(21-16)20-15-6-3-2-5-14(15)19/h2-8,13H,9-12H2,1H3,(H,20,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	381	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32503 (pyridine amide, 18) Show SMILES CC1CCN(CC1)C(=O)c1ccc(CS(=O)(=O)c2c(Cl)cccc2Cl)nc1 Show InChI InChI=1S/C19H20Cl2N2O3S/c1-13-7-9-23(10-8-13)19(24)14-5-6-15(22-11-14)12-27(25,26)18-16(20)3-2-4-17(18)21/h2-6,11,13H,7-10,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32504 (pyridine amide, 19) Show SMILES CC1CCN(CC1)C(=O)c1ccc(CS(=O)(=O)c2c(Cl)cccc2Cl)cn1 Show InChI InChI=1S/C19H20Cl2N2O3S/c1-13-7-9-23(10-8-13)19(24)17-6-5-14(11-22-17)12-27(25,26)18-15(20)3-2-4-16(18)21/h2-6,11,13H,7-10,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32505 (pyridine amide, 20) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCCC1 Show InChI InChI=1S/C17H16Cl2N2O3S/c18-14-4-3-5-15(19)16(14)25(23,24)11-12-8-13(10-20-9-12)17(22)21-6-1-2-7-21/h3-5,8-10H,1-2,6-7,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32510 (pyridine amide, 25) Show SMILES NC(=O)C1CCN(CC1)C(=O)c1cncc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1 Show InChI InChI=1S/C19H19Cl2N3O4S/c20-15-2-1-3-16(21)17(15)29(27,28)11-12-8-14(10-23-9-12)19(26)24-6-4-13(5-7-24)18(22)25/h1-3,8-10,13H,4-7,11H2,(H2,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32517 (pyridine amide, 14) Show SMILES CC1CCN(CC1)C(=O)c1cccc(n1)S(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C18H19ClN2O3S/c1-13-9-11-21(12-10-13)18(22)15-6-4-8-17(20-15)25(23,24)16-7-3-2-5-14(16)19/h2-8,13H,9-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.67E+3	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E] (Homo sapiens (Human))	BDBM32511 (pyridine amide, 26) Show SMILES Clc1cccc(Cl)c1S(=O)(=O)Cc1cncc(c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C17H16Cl2N2O4S/c18-14-2-1-3-15(19)16(14)26(23,24)11-12-8-13(10-20-9-12)17(22)21-4-6-25-7-5-21/h1-3,8-10H,4-7,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	6.5	23
Bristol-Myers Squibb Company					Assay Description 11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...				Bioorg Med Chem Lett 18: 3168-72 (2008) Article DOI: 10.1016/j.bmcl.2008.04.069 BindingDB Entry DOI: 10.7270/Q2P26WGT
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143031 (8'N-[1-carbamoyl-3-phenyl-(1R)-propyl]-2'-benzo[d]...) Show SMILES NC(=O)[C@@H](CCc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:17| Show InChI InChI=1S/C29H32N6O6/c30-25(36)21(8-6-19-4-2-1-3-5-19)32-26(37)22-10-11-29(12-14-31-15-13-29)35-28(39)33(27(38)34(22)35)17-20-7-9-23-24(16-20)41-18-40-23/h1-5,7,9-11,16,21-22,31H,6,8,12-15,17-18H2,(H2,30,36)(H,32,37)/t21-,22?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50344952 ((2R,3S,4R,5R,8R,9S,10S,11R,12S)-5-ethyl-11-((2S,3R...) Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@](C)(C[C@@H](C)O2)OC)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)CC)[C@@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@H]1C |wU:24.24,8.8,29.33,36.38,6.6,20.21,2.1,12.12,26.27,wD:22.23,10.9,30.32,45.48,12.18,43.46,47.51,15.15,c:42,(6.35,-6.68,;6.37,-5.14,;7.71,-4.39,;7.7,-5.93,;9.03,-6.7,;9.01,-8.24,;10.37,-5.93,;11.7,-6.7,;10.37,-4.39,;11.7,-5.16,;13.03,-5.93,;13.03,-7.47,;14.35,-8.24,;13.56,-9.57,;15.69,-7.47,;15.69,-5.95,;17.02,-5.16,;14.36,-5.16,;15.1,-9.57,;16.64,-9.57,;11.71,-3.64,;13.04,-4.42,;11.72,-2.1,;13.05,-1.34,;14.38,-.56,;15.71,-1.31,;17.04,-.56,;18.37,-1.33,;17.04,.98,;15.71,1.77,;14.38,.98,;13.05,1.75,;15.71,3.31,;17.04,4.08,;14.38,4.08,;14.38,5.62,;10.39,-1.31,;11.72,-.54,;10.39,.23,;9.06,1,;9.08,2.54,;7.73,.23,;8.82,-.85,;7.72,-1.31,;6.38,-.54,;6.39,-2.08,;5.06,-1.29,;6.38,-3.62,;5.04,-4.35,)| Show InChI InChI=1S/C38H67NO10/c1-14-28-23(6)30(40)24(7)32-20(3)17-38(11,49-32)34(48-36-31(41)27(39(12)15-2)16-21(4)45-36)25(8)33(26(9)35(42)46-28)47-29-19-37(10,43-13)18-22(5)44-29/h21-31,33-34,36,40-41H,14-19H2,1-13H3/t21-,22-,23+,24-,25+,26-,27+,28-,29+,30+,31-,33+,34-,36+,37+,38-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143037 (CHEMBL411576 | MOTILIN) Show SMILES CCC(C)C(NC(=O)C1CCCN1C(=O)C(NC(=O)C(N)Cc1ccccc1)C(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCSC)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(O)=O)C(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(N)=O)C(O)=O Show InChI InChI=1S/C120H188N34O35S/c1-9-64(6)97(152-114(184)86-31-22-53-154(86)117(187)96(63(4)5)151-99(169)70(123)56-66-23-12-10-13-24-66)115(185)150-84(57-67-25-14-11-15-26-67)113(183)153-98(65(7)155)116(186)149-83(58-68-32-34-69(156)35-33-68)101(171)135-60-91(161)136-75(39-45-93(163)164)105(175)147-82(55-62(2)3)111(181)145-77(37-43-88(125)158)106(176)140-73(29-20-51-132-119(128)129)103(173)146-80(48-54-190-8)110(180)142-76(36-42-87(124)157)107(177)144-79(41-47-95(167)168)108(178)139-72(28-17-19-50-122)102(172)143-78(40-46-94(165)166)109(179)141-74(30-21-52-133-120(130)131)104(174)148-85(59-90(127)160)112(182)138-71(27-16-18-49-121)100(170)134-61-92(162)137-81(118(188)189)38-44-89(126)159/h10-15,23-26,32-35,62-65,70-86,96-98,155-156H,9,16-22,27-31,36-61,121-123H2,1-8H3,(H2,124,157)(H2,125,158)(H2,126,159)(H2,127,160)(H,134,170)(H,135,171)(H,136,161)(H,137,162)(H,138,182)(H,139,178)(H,140,176)(H,141,179)(H,142,180)(H,143,172)(H,144,177)(H,145,181)(H,146,173)(H,147,175)(H,148,174)(H,149,186)(H,150,185)(H,151,169)(H,152,184)(H,153,183)(H,163,164)(H,165,166)(H,167,168)(H,188,189)(H4,128,129,132)(H4,130,131,133)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143033 (CHEMBL46272 | methyl 2-[2'-benzo[d][1,3]dioxol-5-y...) Show SMILES COC(=O)[C@@H](CCc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:18| Show InChI InChI=1S/C30H33N5O7/c1-40-27(37)22(9-7-20-5-3-2-4-6-20)32-26(36)23-11-12-30(13-15-31-16-14-30)35-29(39)33(28(38)34(23)35)18-21-8-10-24-25(17-21)42-19-41-24/h2-6,8,10-12,17,22-23,31H,7,9,13-16,18-19H2,1H3,(H,32,36)/t22-,23?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143032 (8'N-[1-(1-carbamoyl-3-phenylpropylcarbamoyl)-3-phe...) Show SMILES NC(=O)C(CCc1ccccc1)NC(=O)C(CCc1ccccc1)NC(=O)C1CCC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O Show InChI InChI=1S/C39H45N7O7/c40-34(47)29(14-11-26-7-3-1-4-8-26)42-35(48)30(15-12-27-9-5-2-6-10-27)43-36(49)31-17-18-39(19-21-41-22-20-39)46-38(51)44(37(50)45(31)46)24-28-13-16-32-33(23-28)53-25-52-32/h1-10,13,16,23,29-31,41H,11-12,14-15,17-22,24-25H2,(H2,40,47)(H,42,48)(H,43,49)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.350	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143028 (8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...) Show SMILES NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)C1CCC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O Show InChI InChI=1S/C39H45N7O7/c40-34(47)29(14-11-26-7-3-1-4-8-26)42-35(48)30(15-12-27-9-5-2-6-10-27)43-36(49)31-17-18-39(19-21-41-22-20-39)46-38(51)44(37(50)45(31)46)24-28-13-16-32-33(23-28)53-25-52-32/h1-10,13,16,23,29-31,41H,11-12,14-15,17-22,24-25H2,(H2,40,47)(H,42,48)(H,43,49)/t29-,30-,31?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0470	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143038 (8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...) Show SMILES NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:30| Show InChI InChI=1S/C39H43N7O7/c40-34(47)29(14-11-26-7-3-1-4-8-26)42-35(48)30(15-12-27-9-5-2-6-10-27)43-36(49)31-17-18-39(19-21-41-22-20-39)46-38(51)44(37(50)45(31)46)24-28-13-16-32-33(23-28)53-25-52-32/h1-10,13,16-18,23,29-31,41H,11-12,14-15,19-22,24-25H2,(H2,40,47)(H,42,48)(H,43,49)/t29-,30-,31?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.220	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143040 (8'N-[1-carbamoyl-2-phenyl-(1S)-ethyl]-2'-benzo[d][...) Show SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)C1C=CC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |c:16| Show InChI InChI=1S/C28H30N6O6/c29-24(35)20(14-18-4-2-1-3-5-18)31-25(36)21-8-9-28(10-12-30-13-11-28)34-27(38)32(26(37)33(21)34)16-19-6-7-22-23(15-19)40-17-39-22/h1-9,15,20-21,30H,10-14,16-17H2,(H2,29,35)(H,31,36)/t20-,21?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair

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