| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Motilin receptor |
|---|
| Ligand | BDBM50143032 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_122661 (CHEMBL732791) |
|---|
| EC50 | 0.35±n/a nM |
|---|
| Citation |  Li, JJ; Chao, HG; Wang, H; Tino, JA; Lawrence, RM; Ewing, WR; Ma, Z; Yan, M; Slusarchyk, D; Seethala, R; Sun, H; Li, D; Burford, NT; Stoffel, RH; Salyan, ME; Li, CY; Witkus, M; Zhao, N; Rich, A; Gordon, DA Discovery of a potent and novel motilin agonist. J Med Chem47:1704-8 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Motilin receptor |
|---|
| Name: | Motilin receptor |
|---|
| Synonyms: | G-protein coupled receptor 38 | GPR38 | MLNR | MTLR | MTLR1 | MTLR_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 45365.95 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_122664 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
|
|
|
|---|
| BDBM50143032 |
|---|
| n/a |
|---|
| Name | BDBM50143032 |
|---|
| Synonyms: | 8'N-[1-(1-carbamoyl-3-phenylpropylcarbamoyl)-3-phenylpropyl]-2'-benzo[d][1,3]dioxol-5-ylmethyl-1',3'-dioxospiro[hexahydropyridine-4,5'-perhydro[1,2,4]triazolo[1,2-a]pyridazine]-8'-carboxamide | CHEMBL296474 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C39H45N7O7 |
|---|
| Mol. Mass. | 723.8173 |
|---|
| SMILES | NC(=O)C(CCc1ccccc1)NC(=O)C(CCc1ccccc1)NC(=O)C1CCC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
