| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
|---|
| Ligand | BDBM50167683 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_302571 (CHEMBL839532) |
|---|
| Ki | >5000±n/a nM |
|---|
| Citation |  Tian, X; Field, T; Mazur, AW; Ebetino, FH; Wos, JA; Crossdoersen, D; Pinney, BB; Sheldon, RJ Design, synthesis, and evaluation of proline based melanocortin receptor ligands. Bioorg Med Chem Lett15:2819-23 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocyte-stimulating hormone receptor |
|---|
| Name: | Melanocyte-stimulating hormone receptor |
|---|
| Synonyms: | MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 34717.23 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q01726 |
|---|
| Residue: | 317 |
|---|
| Sequence: | MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVV
ATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVI
DVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFI
AYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGA
VTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF
HSQELRRTLKEVLTCSW
|
|
|
|---|
| BDBM50167683 |
|---|
| n/a |
|---|
| Name | BDBM50167683 |
|---|
| Synonyms: | (2S,4S)-4-Benzyl-1-[(S)-5-guanidino-2-(2-naphthalen-2-yl-acetylamino)-pentanoyl]-pyrrolidine-2-carboxylic acid benzylamide | CHEMBL439522 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C37H42N6O3 |
|---|
| Mol. Mass. | 618.7678 |
|---|
| SMILES | NC(=N)NCCC[C@H](NC(=O)Cc1ccc2ccccc2c1)C(=O)N1C[C@@H](Cc2ccccc2)C[C@H]1C(=O)NCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
