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TargetKappa-type opioid receptor
LigandBDBM50216135
Substrate/Competitorn/a
Meas. Tech.ChEMBL_439882 (CHEMBL890203)
Ki 910±n/a nM
Citation Simpson, DS; Katavic, PL; Lozama, A; Harding, WW; Parrish, D; Deschamps, JR; Dersch, CM; Partilla, JS; Rothman, RB; Navarro, H; Prisinzano, TE Synthetic studies of neoclerodane diterpenes from Salvia divinorum: preparation and opioid receptor activity of salvinicin analogues. J Med Chem50:3596-603 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kappa-type opioid receptor
Name:Kappa-type opioid receptor
Synonyms:K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:42648.76
Organism:Homo sapiens (Human)
Description:P41145
Residue:380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50216135
n/a
NameBDBM50216135
Synonyms:(1R,2R,4aR,5R,7S,8aR)-7-acetoxy-5-(methoxycarbonyl)-4a-methyl-8-oxo-1-(2-(tetrahydrofuran-3-yl)ethyl)-decahydronaphthalene-2-carboxylic acid | CHEMBL226677
TypeSmall organic molecule
Emp. Form.C23H34O8
Mol. Mass.438.5113
SMILESCOC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@@H]2[C@@](C)(CCC3CCOC3)[C@@H](CC[C@@]12C)C(O)=O
Structure
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