| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Growth hormone secretagogue receptor type 1 |
|---|
| Ligand | BDBM50376757 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_477813 (CHEMBL931245) |
|---|
| EC50 | 3±n/a nM |
|---|
| Citation |  Li, JJ; Wang, H; Li, J; Qu, F; Swartz, SG; Hernández, AS; Biller, SA; Robl, JA; Tino, JA; Slusarchyk, D; Seethala, R; Sleph, P; Yan, M; Grover, G; Flynn, N; Murphy, BJ; Gordon, D Tetrazole based amides as growth hormone secretagogues. Bioorg Med Chem Lett18:2536-9 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Growth hormone secretagogue receptor type 1 |
|---|
| Name: | Growth hormone secretagogue receptor type 1 |
|---|
| Synonyms: | GH-releasing peptide receptor | GHRP | GHS-R | GHSR | GHSR_HUMAN | Ghrelin Receptor (Growth Hormone Secretagogue Receptor Type 1) | Ghrelin receptor | Ghrelin receptor 1a (GHS-R1a) |
|---|
| Type: | Receptor |
|---|
| Mol. Mass.: | 41334.57 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Receptor binding studies use plasma membranes from LLC PK-1 cells transiently transfected with hGHSR1a. |
|---|
| Residue: | 366 |
|---|
| Sequence: | MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
ESSINT
|
|
|
|---|
| BDBM50376757 |
|---|
| n/a |
|---|
| Name | BDBM50376757 |
|---|
| Synonyms: | CHEMBL409462 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H37N7O5 |
|---|
| Mol. Mass. | 539.6266 |
|---|
| SMILES | CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOc1cccc(c1)C(=O)NCCCCO |
|---|
| Structure | 
|
|---|
Search and Browse
