| Reaction Details |
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 | Report a problem with these data |
| Target | Growth hormone secretagogue receptor type 1 |
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| Ligand | BDBM50376782 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_477813 (CHEMBL931245) |
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| EC50 | 3.1±n/a nM |
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| Citation |  Li, JJ; Wang, H; Li, J; Qu, F; Swartz, SG; Hernández, AS; Biller, SA; Robl, JA; Tino, JA; Slusarchyk, D; Seethala, R; Sleph, P; Yan, M; Grover, G; Flynn, N; Murphy, BJ; Gordon, D Tetrazole based amides as growth hormone secretagogues. Bioorg Med Chem Lett18:2536-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Growth hormone secretagogue receptor type 1 |
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| Name: | Growth hormone secretagogue receptor type 1 |
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| Synonyms: | GH-releasing peptide receptor | GHRP | GHS-R | GHSR | GHSR_HUMAN | Ghrelin Receptor (Growth Hormone Secretagogue Receptor Type 1) | Ghrelin receptor | Ghrelin receptor 1a (GHS-R1a) |
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| Type: | Receptor |
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| Mol. Mass.: | 41334.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding studies use plasma membranes from LLC PK-1 cells transiently transfected with hGHSR1a. |
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| Residue: | 366 |
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| Sequence: | MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
ESSINT
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| BDBM50376782 |
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| n/a |
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| Name | BDBM50376782 |
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| Synonyms: | CHEMBL263389 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H37N7O4 |
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| Mol. Mass. | 523.6272 |
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| SMILES | CN(CCc1cccc(O)c1)C(=O)CCCn1nnnc1[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N |
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| Structure | 
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