| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
|---|
| Ligand | BDBM50335492 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_702118 (CHEMBL1655348) |
|---|
| IC50 | 4600±n/a nM |
|---|
| Citation |  Deng, L; Endo, K; Kato, M; Cheng, G; Yajima, S; Song, Y Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes. ACS Med Chem Lett2:165-170 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
|---|
| Name: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
|---|
| Synonyms: | 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DXP) | 1-Deoxyxylulose 5-phosphate reductoisomerase (DXR) | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) | 2-C-methyl-D-erythritol 4-phosphate synthase | DXP reductoisomerase | DXR_ECOLI | dxr | ispC | yaeM |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 43384.52 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P45568 |
|---|
| Residue: | 398 |
|---|
| Sequence: | MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVEQCLEFSPRYAVMDDEA
SAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIVGAAGLLPTLAAIRAGKTI
LLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSLPQPIQHNLGYADLEQNGVVS
ILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKISVDSATMMNKGLEYIEARWLFN
ASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVNSGVKPLDFC
KLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAALN
LSVLEKMDMREPQCVDDVLSVDANAREVARKEVMRLAS
|
|
|
|---|
| BDBM50335492 |
|---|
| n/a |
|---|
| Name | BDBM50335492 |
|---|
| Synonyms: | (pyridin-2-ylmethyl)phosphonic acid | CHEMBL1615245 | Pyridin-2-ylmethylphosphonic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H8NO3P |
|---|
| Mol. Mass. | 173.1064 |
|---|
| SMILES | OP(O)(=O)Cc1ccccn1 |
|---|
| Structure | 
|
|---|
Search and Browse
