| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50387897 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_830702 (CHEMBL2061689) |
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| EC50 | 268±n/a nM |
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| Citation |  Sakairi, M; Kogami, M; Torii, M; Kataoka, H; Fujieda, H; Makino, M; Kataoka, D; Okamoto, R; Miyazawa, T; Okabe, M; Inoue, M; Takahashi, N; Harada, S; Watanabe, N Synthesis and SAR studies of bicyclic amine series GPR119 agonists. Bioorg Med Chem Lett22:5123-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50387897 |
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| n/a |
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| Name | BDBM50387897 |
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| Synonyms: | CHEMBL2058397 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H30N4O4S |
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| Mol. Mass. | 410.531 |
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| SMILES | CC(C)(C)OC(=O)N1CCC(CCCNc2ccc3c(NNS3(=O)=O)c2)CC1 |
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| Structure | 
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