| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
|---|
| Ligand | BDBM50390231 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_834924 (CHEMBL2073334) |
|---|
| IC50 | 1.9±n/a nM |
|---|
| Citation |  Tamura, Y; Omori, N; Kouyama, N; Nishiura, Y; Hayashi, K; Watanabe, K; Tanaka, Y; Chiba, T; Yukioka, H; Sato, H; Okuno, T Design, synthesis and identification of novel benzimidazole derivatives as highly potent NPY Y5 receptor antagonists with attractive in vitro ADME profiles. Bioorg Med Chem Lett22:5498-502 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 5 |
|---|
| Name: | Neuropeptide Y receptor type 5 |
|---|
| Synonyms: | NPY-Y5 | NPY5R_MOUSE | Neuropeptide Y receptor Y5 | Neuropeptide Y receptor type 5 (NPY Y5) | Npy5 | Npy5r |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52807.91 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | O70342 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDD
LQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTL
TSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFL
IATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQ
YILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSY
SFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVK
PEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISN
RHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
|
|
|
|---|
| BDBM50390231 |
|---|
| n/a |
|---|
| Name | BDBM50390231 |
|---|
| Synonyms: | CHEMBL2070158 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H19N3O3S |
|---|
| Mol. Mass. | 393.459 |
|---|
| SMILES | CCCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(=O)n(c1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
