| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50404982 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39350 (CHEMBL654957) |
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| Kd | 1.6±n/a nM |
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| Citation |  Baldwin, JJ; Denny, GH; Hirschmann, R; Freedman, MB; Ponticello, GS; Gross, DM; Sweet, CS Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class. J Med Chem26:950-7 (1983) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1 | Adrenergic receptor | adrenergic Beta1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50540.48 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73 |
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| Residue: | 467 |
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| Sequence: | MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAG
MGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVC
TVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRR
PSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANS
AFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDE
DEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
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| BDBM50404982 |
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| n/a |
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| Name | BDBM50404982 |
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| Synonyms: | CHEMBL366769 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25N3O2S |
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| Mol. Mass. | 371.496 |
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| SMILES | CC(C)(C)NCC(O)COc1ccc(cc1)-c1nc(c[nH]1)-c1cccs1 |
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| Structure | 
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