| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM25756 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_38001 (CHEMBL651635) |
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| Kd | 162.18±n/a nM |
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| Citation |  Baldwin, JJ; Denny, GH; Hirschmann, R; Freedman, MB; Ponticello, GS; Gross, DM; Sweet, CS Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class. J Med Chem26:950-7 (1983) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_CAVPO | Adrb2 | adrenergic Beta2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46993.24 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 |
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| Residue: | 418 |
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| Sequence: | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
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| BDBM25756 |
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| n/a |
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| Name | BDBM25756 |
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| Synonyms: | (2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol | Betalok | CHEMBL13 | Metoprolol | Spesicor | Spesikor | metoprolol tartrate | {2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}(propan-2-yl)amine |
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| Type | Small organic molecule |
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| Emp. Form. | C15H25NO3 |
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| Mol. Mass. | 267.3639 |
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| SMILES | COCCc1ccc(OCC(O)CNC(C)C)cc1 |
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| Structure | 
|
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