| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
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| Ligand | BDBM50424177 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_933559 (CHEMBL2319721) |
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| IC50 | 41±n/a nM |
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| Citation |  Tamura, Y; Hayashi, K; Omori, N; Nishiura, Y; Watanabe, K; Tanaka, N; Fujioka, M; Kouyama, N; Yukimasa, A; Tanaka, Y; Chiba, T; Tanioka, H; Nambu, H; Yukioka, H; Sato, H; Okuno, T Identification of a novel benzimidazole derivative as a highly potent NPY Y5 receptor antagonist with an anti-obesity profile. Bioorg Med Chem Lett23:90-5 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 5 |
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| Name: | Neuropeptide Y receptor type 5 |
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| Synonyms: | NPY-Y5 | NPY5R_MOUSE | Neuropeptide Y receptor Y5 | Neuropeptide Y receptor type 5 (NPY Y5) | Npy5 | Npy5r |
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| Type: | Enzyme |
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| Mol. Mass.: | 52807.91 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | O70342 |
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| Residue: | 466 |
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| Sequence: | MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDD
LQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTL
TSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFL
IATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQ
YILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSY
SFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVK
PEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISN
RHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
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| BDBM50424177 |
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| n/a |
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| Name | BDBM50424177 |
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| Synonyms: | CHEMBL2312068 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13F3N2O3S |
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| Mol. Mass. | 370.346 |
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| SMILES | CCS(=O)(=O)c1ccc2nc(Oc3cccc(c3)C(F)(F)F)[nH]c2c1 |
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| Structure | 
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