| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium channel subfamily K member 9 |
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| Ligand | BDBM50426570 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938658 (CHEMBL2327430) |
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| IC50 | 35±n/a nM |
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| Citation |  Bagal, SK; Brown, AD; Cox, PJ; Omoto, K; Owen, RM; Pryde, DC; Sidders, B; Skerratt, SE; Stevens, EB; Storer, RI; Swain, NA Ion channels as therapeutic targets: a drug discovery perspective. J Med Chem56:593-624 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium channel subfamily K member 9 |
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| Name: | Potassium channel subfamily K member 9 |
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| Synonyms: | Acid-sensitive potassium channel protein TASK-3 | KCNK9 | KCNK9_HUMAN | TASK3 | TWIK-related acid-sensitive K(+) channel 3 | Two pore K(+) channel KT3.2 | Two pore potassium channel KT3.2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42276.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1457494 |
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| Residue: | 374 |
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| Sequence: | MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR
QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL
TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ
CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN
LVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCT
CYRSQDYGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLFPSPISSISPGLHS
FTDHQRLMKRRKSV
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| BDBM50426570 |
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| n/a |
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| Name | BDBM50426570 |
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| Synonyms: | CHEMBL2324344 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H32N4O2 |
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| Mol. Mass. | 468.59 |
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| SMILES | CCCC(=O)C1CCN(CC1)c1ncnc2CCN(Cc12)C(=O)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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