| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily C member 1 |
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| Ligand | BDBM50254790 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938832 (CHEMBL2328101) |
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| IC50 | 800±n/a nM |
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| Citation |  Bagal, SK; Brown, AD; Cox, PJ; Omoto, K; Owen, RM; Pryde, DC; Sidders, B; Skerratt, SE; Stevens, EB; Storer, RI; Swain, NA Ion channels as therapeutic targets: a drug discovery perspective. J Med Chem56:593-624 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily C member 1 |
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| Name: | Potassium voltage-gated channel subfamily C member 1 |
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| Synonyms: | KCNC1_RAT | Kcnc1 | NGK2 | RAW2 | Voltage-gated potassium channel subunit Kv3.1 | Voltage-gated potassium channel subunit Kv4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 65852.49 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_938832 |
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| Residue: | 585 |
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| Sequence: | MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRH
PGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALD
SFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALF
EDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAE
TEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSS
KAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFA
TMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALC
ALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPH
HSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQALTPDEGLPFTRSGTR
ERYGPCFLLSTGEYACPPGGGMRKDLCKESPVIAKYMPTEAVRVT
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| BDBM50254790 |
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| n/a |
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| Name | BDBM50254790 |
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| Synonyms: | (S)-Norfluoxetine | CHEMBL465123 | NORFLUOXETINE |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16F3NO |
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| Mol. Mass. | 295.2995 |
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| SMILES | NCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1 |r| |
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| Structure | 
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