| Reaction Details |
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 | Report a problem with these data |
| Target | 5'-nucleotidase |
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| Ligand | BDBM50443528 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1275399 (CHEMBL3090248) |
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| IC50 | 44300±n/a nM |
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| Citation |  Iqbal, J; Saeed, A; Raza, R; Matin, A; Hameed, A; Furtmann, N; Lecka, J; Sévigny, J; Bajorath, J Identification of sulfonic acids as efficient ecto-5'-nucleotidase inhibitors. Eur J Med Chem70:685-91 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5'-nucleotidase |
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| Name: | 5'-nucleotidase |
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| Synonyms: | 5'-nucleotidase | 5NTD_RAT | Ecto-5'-nucleotidase (e5'NT) | Ecto-5-nucleotidase (e5'NT) | NT | Nt5 | Nt5e | Nte |
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| Type: | Enzyme |
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| Mol. Mass.: | 63971.44 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P21588 |
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| Residue: | 576 |
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| Sequence: | MRPAAATAPKWLLLALSALLPLWPTAKSWELTIMHTNDVHSRLEQTSDDSTKCLNASLCV
GGVARLFTKVQQIRKEEPNVLLLDAGDQYQGTIWFTVYKGLEVAHFMNLLGYDAMALGNH
EFDNGVEGLIDPLLRNVKFPILSANIKARGPLAPQISGLYLPYKVLSVGGEVVGIVGYTS
KETPFLSNPGTNLVFEDEVTALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDV
VVGGHTNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDDKG
NVVTSYGNPILLNSTIREDAAIKADINQWRIKLDNYSTQELGRTIVYLNGSAQECRFREC
NMGNLICDAMINNNLRHPDEMFWNHVSMCIVNGGGIRSPIDERNNGTITWENLAAVLPFG
GTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDISRKPWDRVVQLKVLCTK
CRVPIYEPLEMDKVYKVVLPSYLVNGGDGFQMIKDELLKHDSGDQDISVVSEYISKMKVI
YPAVEGRIKFSAASHYQGSFPLIILSFWAVILVLYQ
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| BDBM50443528 |
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| n/a |
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| Name | BDBM50443528 |
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| Synonyms: | CHEMBL3088000 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H10N2O4S |
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| Mol. Mass. | 254.262 |
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| SMILES | Cc1cc(=O)n([nH]1)-c1ccc(cc1)S(O)(=O)=O |
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| Structure | 
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