Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H3 receptor | ||
| Ligand | BDBM50444511 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1277742 | ||
| Ki | 4.0±n/a nM | ||
| Citation |  Wilson DM; Apps J; Bailey N; Bamford MJ; Beresford IJ; Brackenborough K; Briggs MA; Brough S; Calver AR; Crook B; Davis RK; Davis RP; Davis S; Dean DK; Harris L; Heslop T; Holland V; Jeffrey P; Panchal TA; Parr CA; Quashie N; Schogger J; Sehmi SS; Stean TO; Steadman JG; Trail B; Wald J; Worby A; Takle AK; Witherington J; Medhurst AD Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonists. Bioorg Med Chem Lett 23:6890-6 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histamine H3 receptor | |||
| Name: | Histamine H3 receptor | ||
| Synonyms: | HH3R | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 48607.98 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | n/a | ||
| Residue: | 445 | ||
| Sequence: |
| ||
| BDBM50444511 | |||
| n/a | |||
| Name | BDBM50444511 | ||
| Synonyms: | CHEMBL3092838 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H23N3O | ||
| Mol. Mass. | 333.4268 | ||
| SMILES | Cc1nc(Oc2ccc3CCN(CCc3c2)C2CCC2)ccc1C#N | ||
| Structure | 
| ||