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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neurotensin receptor type 1 | ||
| Ligand | BDBM50444948 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1281497 (CHEMBL3101955) | ||
| EC50 | 9200±n/a nM | ||
| Citation |  Hershberger, PM; Hedrick, MP; Peddibhotla, S; Mangravita-Novo, A; Gosalia, P; Li, Y; Gray, W; Vicchiarelli, M; Smith, LH; Chung, TD; Thomas, JB; Caron, MG; Pinkerton, AB; Barak, LS; Roth, GP Imidazole-derived agonists for the neurotensin 1 receptor. Bioorg Med Chem Lett24:262-7 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neurotensin receptor type 1 | |||
| Name: | Neurotensin receptor type 1 | ||
| Synonyms: | Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 46278.89 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1453811 | ||
| Residue: | 418 | ||
| Sequence: |
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| BDBM50444948 | |||
| n/a | |||
| Name | BDBM50444948 | ||
| Synonyms: | CHEMBL3099768 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H27ClN4O3 | ||
| Mol. Mass. | 490.981 | ||
| SMILES | CC(C)C[C@H](NC(=O)c1cn(c(n1)-c1c(C)cccc1C)-c1ccnc2cc(Cl)ccc12)C(O)=O |r,wD:4.4,(40.52,-45.74,;41.15,-44.33,;42.68,-44.17,;40.24,-43.09,;40.86,-41.68,;39.95,-40.44,;38.42,-40.6,;37.8,-42.01,;37.51,-39.36,;37.99,-37.89,;36.74,-36.99,;35.5,-37.9,;35.97,-39.36,;33.97,-37.77,;33.1,-39.04,;33.76,-40.43,;31.57,-38.92,;30.9,-37.53,;31.77,-36.26,;33.31,-36.38,;34.18,-35.11,;36.74,-35.45,;35.41,-34.68,;35.41,-33.13,;36.74,-32.36,;38.07,-33.12,;39.39,-32.35,;40.73,-33.1,;42.06,-32.32,;40.75,-34.66,;39.41,-35.43,;38.07,-34.67,;42.39,-41.51,;43.31,-42.76,;43.02,-40.11,)| | ||
| Structure | 
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