| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neurotensin receptor type 1 |
|---|
| Ligand | BDBM50444951 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1281497 (CHEMBL3101955) |
|---|
| EC50 | >80000±n/a nM |
|---|
| Citation |  Hershberger, PM; Hedrick, MP; Peddibhotla, S; Mangravita-Novo, A; Gosalia, P; Li, Y; Gray, W; Vicchiarelli, M; Smith, LH; Chung, TD; Thomas, JB; Caron, MG; Pinkerton, AB; Barak, LS; Roth, GP Imidazole-derived agonists for the neurotensin 1 receptor. Bioorg Med Chem Lett24:262-7 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neurotensin receptor type 1 |
|---|
| Name: | Neurotensin receptor type 1 |
|---|
| Synonyms: | Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 46278.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1453811 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
|
|
|
|---|
| BDBM50444951 |
|---|
| n/a |
|---|
| Name | BDBM50444951 |
|---|
| Synonyms: | CHEMBL3099782 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H22N4O3 |
|---|
| Mol. Mass. | 378.4244 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)c1cn(c(n1)-c1ccccc1)-c1ccncc1)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
