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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neurotensin receptor type 1 | ||
| Ligand | BDBM50444959 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1281497 (CHEMBL3101955) | ||
| EC50 | 9400±n/a nM | ||
| Citation |  Hershberger, PM; Hedrick, MP; Peddibhotla, S; Mangravita-Novo, A; Gosalia, P; Li, Y; Gray, W; Vicchiarelli, M; Smith, LH; Chung, TD; Thomas, JB; Caron, MG; Pinkerton, AB; Barak, LS; Roth, GP Imidazole-derived agonists for the neurotensin 1 receptor. Bioorg Med Chem Lett24:262-7 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neurotensin receptor type 1 | |||
| Name: | Neurotensin receptor type 1 | ||
| Synonyms: | Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 46278.89 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1453811 | ||
| Residue: | 418 | ||
| Sequence: |
| ||
| BDBM50444959 | |||
| n/a | |||
| Name | BDBM50444959 | ||
| Synonyms: | CHEMBL3099774 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H27ClN4O5 | ||
| Mol. Mass. | 522.98 | ||
| SMILES | COc1cccc(OC)c1-c1nc(cn1-c1ccnc2cc(Cl)ccc12)C(=O)N[C@H](CC(C)C)C(O)=O |r,wU:29.32,(16.64,-10.24,;17.78,-9.2,;17.46,-7.7,;15.99,-7.23,;15.66,-5.72,;16.81,-4.69,;18.27,-5.16,;19.42,-4.13,;19.1,-2.62,;18.59,-6.67,;20.05,-7.14,;20.53,-8.6,;22.07,-8.6,;22.54,-7.13,;21.3,-6.23,;21.3,-4.69,;19.96,-3.92,;19.97,-2.38,;21.29,-1.61,;22.63,-2.37,;23.96,-1.6,;25.29,-2.36,;26.62,-1.58,;25.3,-3.91,;23.97,-4.68,;22.63,-3.91,;22.98,-9.84,;22.36,-11.25,;24.51,-9.68,;25.42,-10.92,;24.8,-12.33,;25.7,-13.58,;25.08,-14.98,;27.24,-13.41,;26.95,-10.76,;27.86,-12,;27.58,-9.35,)| | ||
| Structure | 
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