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TargetD(1A) dopamine receptor
LigandBDBM50004822
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1353324 (CHEMBL3267826)
Ki 73±n/a nM
Citation Liu, Z; Ai, J; Peng, X; Song, Z; Wu, K; Zhang, J; Yao, Q; Chen, Y; Ji, Y; Yang, Y; Geng, M; Zhang, A Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities. ACS Med Chem Lett5:304-8 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(1A) dopamine receptor
Name:D(1A) dopamine receptor
Synonyms:DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:Enzyme
Mol. Mass.:49303.43
Organism:Homo sapiens (Human)
Description:P21728
Residue:446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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  Blast E-value cutoff:
BDBM50004822
n/a
NameBDBM50004822
Synonyms:(R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | (R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium | 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393) | 7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393) | CHEMBL1467585 | CHEMBL24077 | R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | SK&F-383933 | SK-38393 | SK-383933 | SKF 38393 | SKF 38393 (+)
TypeSmall organic molecule
Emp. Form.C16H17NO2
Mol. Mass.255.3117
SMILESOc1cc2CCNC[C@H](c3ccccc3)c2cc1O
Structure
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