Reaction Details |
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Target | Env polyprotein |
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Ligand | BDBM50023611 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1455142 (CHEMBL3366755) |
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EC50 | 1.3±n/a nM |
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Citation | Wang, C; Lu, L; Na, H; Li, X; Wang, Q; Jiang, X; Xu, X; Yu, F; Zhang, T; Li, J; Zhang, Z; Zheng, B; Liang, G; Cai, L; Jiang, S; Liu, K Conjugation of a nonspecific antiviral sapogenin with a specific HIV fusion inhibitor: a promising strategy for discovering new antiviral therapeutics. J Med Chem57:7342-54 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Env polyprotein |
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Name: | Env polyprotein |
Synonyms: | ENV | GP41 | HIV1 |
Type: | PROTEIN |
Mol. Mass.: | 14017.92 |
Organism: | Human immunodeficiency virus 1 |
Description: | ChEMBL_109731 |
Residue: | 124 |
Sequence: | FLGFLGAAGSTMGAASITLTVQARTLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQA
RVLAVERYLQDQQLLGIWGCSGKHICTTTVPWNSSWSNKSLEEIWQNMTWMEWEREIDNY
TGLI
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BDBM50023611 |
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n/a |
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Name | BDBM50023611 |
Synonyms: | CHEMBL2380932 |
Type | Small organic molecule |
Emp. Form. | C186H283N51O64S |
Mol. Mass. | 4289.606 |
SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r| |
Structure |
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