| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 39 |
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| Ligand | BDBM50030784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1438503 (CHEMBL3384907) |
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| EC50 | 1181±n/a nM |
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| Citation |  Peukert, S; Hughes, R; Nunez, J; He, G; Yan, Z; Jain, R; Llamas, L; Luchansky, S; Carlson, A; Liang, G; Kunjathoor, V; Pietropaolo, M; Shapiro, J; Castellana, A; Wu, X; Bose, A Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists. ACS Med Chem Lett5:1114-8 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 39 |
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| Name: | G-protein coupled receptor 39 |
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| Synonyms: | GPR39 | GPR39_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51351.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107977 |
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| Residue: | 453 |
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| Sequence: | MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK
KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY
ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL
VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF
MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ
IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC
CRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQ
SKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
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| BDBM50030784 |
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| n/a |
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| Name | BDBM50030784 |
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| Synonyms: | CHEMBL3342369 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22N6O |
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| Mol. Mass. | 362.4283 |
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| SMILES | CNc1nc(NCc2ccc(cc2)N(C)C(C)=O)cc(n1)-c1ccccn1 |
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| Structure | 
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