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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Nociceptin receptor | ||
| Ligand | BDBM50100985 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1452449 (CHEMBL3362473) | ||
| Ki | 1600±n/a nM | ||
| Citation |  Schunk, S; Linz, K; Frormann, S; Hinze, C; Oberbörsch, S; Sundermann, B; Zemolka, S; Englberger, W; Germann, T; Christoph, T; Kögel, BY; Schröder, W; Harlfinger, S; Saunders, D; Kless, A; Schick, H; Sonnenschein, H Discovery of Spiro[cyclohexane-dihydropyrano[3,4-b]indole]-amines as Potent NOP and Opioid Receptor Agonists. ACS Med Chem Lett5:851-6 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Nociceptin receptor | |||
| Name: | Nociceptin receptor | ||
| Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40702.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41146 | ||
| Residue: | 370 | ||
| Sequence: |
| ||
| BDBM50100985 | |||
| n/a | |||
| Name | BDBM50100985 | ||
| Synonyms: | CHEMBL3325746 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H28ClNO | ||
| Mol. Mass. | 345.906 | ||
| SMILES | Cl.CN(C)[C@@]1(CC[C@@](O)(Cc2ccccc2)CC1)c1ccccc1 |r,wU:4.2,wD:7.7,(42.29,-10.61,;38.63,-8.82,;37.29,-8.05,;37.29,-6.5,;35.96,-8.82,;35.18,-7.49,;33.64,-7.5,;32.87,-8.83,;31.53,-8.06,;31.54,-9.61,;31.55,-11.14,;30.23,-11.91,;30.24,-13.45,;31.58,-14.21,;32.91,-13.42,;32.89,-11.89,;33.64,-10.16,;35.19,-10.16,;36.75,-10.15,;36.01,-11.49,;36.81,-12.81,;38.35,-12.78,;39.09,-11.42,;38.29,-10.11,)| | ||
| Structure | 
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