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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Delta-type opioid receptor | ||
| Ligand | BDBM50101095 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1453328 (CHEMBL3366612) | ||
| Ki | 18±n/a nM | ||
| Citation |  Schunk, S; Linz, K; Hinze, C; Frormann, S; Oberbörsch, S; Sundermann, B; Zemolka, S; Englberger, W; Germann, T; Christoph, T; Kögel, BY; Schröder, W; Harlfinger, S; Saunders, D; Kless, A; Schick, H; Sonnenschein, H Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol. ACS Med Chem Lett5:857-62 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Delta-type opioid receptor | |||
| Name: | Delta-type opioid receptor | ||
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40382.98 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. | ||
| Residue: | 372 | ||
| Sequence: |
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| BDBM50101095 | |||
| n/a | |||
| Name | BDBM50101095 | ||
| Synonyms: | CHEMBL3325957 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H35FN2O8 | ||
| Mol. Mass. | 570.6059 | ||
| SMILES | OC(=O)CC(O)(CC(O)=O)C(O)=O.CN(C)[C@]1(CC[C@@]2(CC1)OCCc1c2[nH]c2ccc(F)cc12)c1ccccc1 |r,wU:16.14,wD:19.21,(30.28,-8.84,;31.61,-9.6,;32.93,-8.84,;31.61,-11.13,;30.28,-11.9,;28.96,-11.13,;31.04,-13.22,;32.57,-13.22,;33.33,-14.55,;33.34,-11.9,;29.52,-13.21,;30.28,-14.54,;27.99,-13.21,;23.02,-15.74,;21.53,-16.15,;20.43,-15.06,;21.14,-17.65,;20.36,-18.98,;18.83,-18.97,;18.07,-17.64,;18.83,-16.31,;20.37,-16.32,;17.16,-18.9,;15.61,-18.74,;14.99,-17.32,;15.89,-16.07,;17.44,-16.24,;18.07,-14.82,;16.92,-13.78,;16.92,-12.23,;15.58,-11.46,;14.24,-12.24,;12.91,-11.46,;14.24,-13.78,;15.58,-14.55,;22.67,-17.66,;23.44,-19,;24.98,-19.01,;25.76,-17.68,;24.99,-16.33,;23.45,-16.33,)| | ||
| Structure | 
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