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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Nociceptin receptor | ||
| Ligand | BDBM50101097 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1453323 (CHEMBL3366607) | ||
| Ki | 11±n/a nM | ||
| Citation |  Schunk, S; Linz, K; Hinze, C; Frormann, S; Oberbörsch, S; Sundermann, B; Zemolka, S; Englberger, W; Germann, T; Christoph, T; Kögel, BY; Schröder, W; Harlfinger, S; Saunders, D; Kless, A; Schick, H; Sonnenschein, H Discovery of a Potent Analgesic NOP and Opioid Receptor Agonist: Cebranopadol. ACS Med Chem Lett5:857-62 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Nociceptin receptor | |||
| Name: | Nociceptin receptor | ||
| Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40702.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41146 | ||
| Residue: | 370 | ||
| Sequence: |
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| BDBM50101097 | |||
| n/a | |||
| Name | BDBM50101097 | ||
| Synonyms: | CHEMBL3325959 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H33FN2O8 | ||
| Mol. Mass. | 556.5793 | ||
| SMILES | OC(=O)CC(O)(CC(O)=O)C(O)=O.CN[C@]1(CC[C@@]2(CC1)OCCc1c2[nH]c2ccc(F)cc12)c1ccccc1 |r,wU:15.13,wD:18.20,(31.05,-21.3,;32.37,-22.06,;33.7,-21.3,;32.37,-23.59,;31.05,-24.35,;29.73,-23.59,;31.81,-25.67,;33.33,-25.68,;34.09,-27,;34.1,-24.36,;30.29,-25.67,;31.05,-26.99,;28.76,-25.66,;22.12,-24.26,;23.22,-25.34,;22.83,-26.85,;22.05,-28.17,;20.52,-28.17,;19.76,-26.83,;20.52,-25.5,;22.06,-25.51,;18.85,-28.09,;17.31,-27.93,;16.68,-26.52,;17.59,-25.27,;19.13,-25.43,;19.76,-24.02,;18.61,-22.98,;18.61,-21.42,;17.27,-20.66,;15.94,-21.43,;14.6,-20.66,;15.93,-22.98,;17.27,-23.75,;24.36,-26.85,;25.13,-28.2,;26.67,-28.2,;27.45,-26.87,;26.68,-25.52,;25.14,-25.52,)| | ||
| Structure | 
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