| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic triacylglycerol lipase |
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| Ligand | BDBM50193723 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1512589 (CHEMBL3610636) |
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| IC50 | 9000±n/a nM |
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| Citation |  Jo, YH; Kim, SB; Liu, Q; Lee, JW; Hwang, BY; Lee, MK Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activity. Bioorg Med Chem Lett25:3455-7 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pancreatic triacylglycerol lipase |
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| Name: | Pancreatic triacylglycerol lipase |
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| Synonyms: | LIPP_PIG | PL | PNLIP | PTL | Pancreatic lipase | Pancreatic triacylglycerol lipase |
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| Type: | Enzyme |
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| Mol. Mass.: | 50080.69 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P00591 |
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| Residue: | 450 |
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| Sequence: | SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTI
TNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQ
NIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAE
PCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQK
NILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPC
PSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSL
FGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASK
ITVERNDGKVYDFCSQETVREEVLLTLNPC
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| BDBM50193723 |
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| n/a |
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| Name | BDBM50193723 |
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| Synonyms: | (S)-2-(2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl)-5,7-dihydroxy-6-(3-methylbut-2-enyl)chroman-4-one | CHEMBL218741 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28O6 |
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| Mol. Mass. | 424.4862 |
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| SMILES | [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(-[#6@@H]-2-[#6]-[#6](=O)-c3c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc3-[#8]-2)c(-[#8])cc1-[#8] |
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| Structure | 
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