| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50156543 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1570606 (CHEMBL3794974) |
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| EC50 | 9.0±n/a nM |
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| Citation |  Ogawa, S; Watanabe, T; Moriyuki, K; Goto, Y; Yamane, S; Watanabe, A; Tsuboi, K; Kinoshita, A; Okada, T; Takeda, H; Tani, K; Maruyama, T Structural optimization and structure-functional selectivity relationship studies of G protein-biased EP2 receptor agonists. Bioorg Med Chem Lett26:2446-9 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39775.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43116 |
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| Residue: | 358 |
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| Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
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| BDBM50156543 |
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| n/a |
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| Name | BDBM50156543 |
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| Synonyms: | CHEMBL3793045 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20F3NO5S |
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| Mol. Mass. | 443.437 |
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| SMILES | [H][C@]12C[C@@H](O)[C@H](COc3cccc(c3)C(F)(F)F)[C@@]1([H])CC[C@@H](O2)c1nc(cs1)C(O)=O |r| |
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| Structure | 
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