| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 17B |
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| Ligand | BDBM50166149 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1575376 (CHEMBL3802094) |
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| IC50 | 290±n/a nM |
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| Citation |  Jung, ME; Byun, BJ; Kim, HM; Lee, JY; Park, JH; Lee, N; Son, YH; Choi, SU; Yang, KM; Kim, SJ; Lee, K; Kim, YC; Choi, G Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening. Bioorg Med Chem Lett26:2719-23 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase 17B |
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| Name: | Serine/threonine-protein kinase 17B |
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| Synonyms: | DRAK2 | ST17B_HUMAN | STK17B | Serine/threonine-protein kinase 17B | Serine/threonine-protein kinase 17B (STK17B) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42332.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O94768 |
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| Residue: | 372 |
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| Sequence: | MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
PNPHELVSDLLC
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| BDBM50166149 |
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| n/a |
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| Name | BDBM50166149 |
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| Synonyms: | CHEMBL3797817 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H15FN4O3 |
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| Mol. Mass. | 414.3886 |
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| SMILES | O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(NC(=O)c3ccccc3F)cc12 |
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| Structure | 
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