| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 2 |
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| Ligand | BDBM50172349 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1579541 (CHEMBL3810887) |
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| IC50 | >100000±n/a nM |
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| Citation |  Chen, H; Yang, H; Wang, Z; Xie, X; Nan, F Discovery of 3-Substituted 1H-Indole-2-carboxylic Acid Derivatives as a Novel Class of CysLT1 Selective Antagonists. ACS Med Chem Lett7:335-9 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 2 |
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| Name: | Cysteinyl leukotriene receptor 2 |
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| Synonyms: | CLTR2_HUMAN | CYSLT2 | CYSLT2R | CYSLTR2 | Cysteinyl leukotriene receptor | Cysteinyl leukotriene receptor 2 | Leukotriene Cysteinyl 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39657.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Leukotriene Cysteinyl 2 CYSLTR2 HUMAN::Q9NS75 |
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| Residue: | 346 |
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| Sequence: | MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSI
YVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYV
NMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQ
NGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRV
SHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACF
NPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV
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| BDBM50172349 |
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| n/a |
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| Name | BDBM50172349 |
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| Synonyms: | CHEMBL3808880 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H18Cl3N3O3 |
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| Mol. Mass. | 562.831 |
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| SMILES | OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1\C=C\C(=O)Nc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |
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| Structure | 
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