| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-serine O-palmitoleoyltransferase porcupine |
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| Ligand | BDBM50205500 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1628389 (CHEMBL3870974) |
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| EC50 | 0.130000±n/a nM |
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| Citation |  You, L; Zhang, C; Yarravarapu, N; Morlock, L; Wang, X; Zhang, L; Williams, NS; Lum, L; Chen, C Development of a triazole class of highly potent Porcn inhibitors. Bioorg Med Chem Lett26:5891-5895 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-serine O-palmitoleoyltransferase porcupine |
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| Name: | Protein-serine O-palmitoleoyltransferase porcupine |
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| Synonyms: | PORCN_MOUSE | Porc | Porcn | Ppn | Probable protein-cysteine N-palmitoyltransferase porcupine | Protein-cysteine N-palmitoyltransferase porcupine | mPORC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52528.36 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_941167 |
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| Residue: | 461 |
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| Sequence: | MATFSRQEFFQQLLQGCLLPTVQQGLDQIWLLLTICFACRLLWRLGLPSYLKHASTVAGG
FFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLSVTILIYLLMGEMHMVDTVTW
HKMRGAQMIVAMKAVSLGFDLDRGEVGAVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAV
QGRPLSRRWLKKVARSLALALLCLVLSTCVGPYLFPYFIPLDGDRLLRNKKRKARGTMVR
WLRAYESAVSFHFSNYFVGFLSEATATLAGAGFTEEKDHLEWDLTVSRPLNVELPRSMVE
VVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLHGFSFHLAAVLLSLAFITYV
EHVLRKRLAQILSACILSKRCLPDCSHRHRLGLGVRALNLLFGALAIFHLSYLGSLFDVD
VDDTTEEQGYGMAYTVHKWSELSWASHWVTFGCWIFYRLIG
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| BDBM50205500 |
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| n/a |
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| Name | BDBM50205500 |
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| Synonyms: | CHEMBL3933984 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H19FN6O |
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| Mol. Mass. | 450.4671 |
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| SMILES | Fc1cnccc1-c1nnn(CC(=O)Nc2ccc(cn2)-c2ccccc2)c1-c1ccccc1 |
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| Structure | 
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