| Reaction Details |
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 | Report a problem with these data |
| Target | Translocator protein |
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| Ligand | BDBM50210943 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1635860 (CHEMBL3878758) |
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| IC50 | 1.6±n/a nM |
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| Citation |  Kim, T; Yang, HY; Park, BG; Jung, SY; Park, JH; Park, KD; Min, SJ; Tae, J; Yang, H; Cho, S; Cho, SJ; Song, H; Mook-Jung, I; Lee, J; Pae, AN Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease. Eur J Med Chem125:1172-1192 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Translocator protein |
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| Name: | Translocator protein |
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| Synonyms: | BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 18834.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30536 |
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| Residue: | 169 |
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| Sequence: | MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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| BDBM50210943 |
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| n/a |
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| Name | BDBM50210943 |
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| Synonyms: | CHEMBL3970955 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22FNO4 |
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| Mol. Mass. | 395.4235 |
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| SMILES | COc1ccc(OC)c(CN(C(C)=O)c2ccc(F)cc2Oc2ccccc2)c1 |
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| Structure | 
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