Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSimilar to alpha-tubulin isoform 1
LigandBDBM50230756
Substrate/Competitorn/a
Meas. Tech.ChEMBL_211322 (CHEMBL818981)
IC50>100000±n/a nM
Citation Terada, TFujimoto, KNomura, MYamashita, JWierzba, KYamazaki, RShibata, JSugimoto, YYamada, YKobunai, T Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents. J Med Chem36:1689-99 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Similar to alpha-tubulin isoform 1
Name:Similar to alpha-tubulin isoform 1
Synonyms:Similar to alpha-tubulin isoform 1
Type:PROTEIN
Mol. Mass.:10383.05
Organism:Bos taurus
Description:ChEMBL_104716
Residue:99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50230756
n/a
NameBDBM50230756
Synonyms:CHEMBL1202598
TypeSmall organic molecule
Emp. Form.C29H40Cl2N2O7
Mol. Mass.599.543
SMILESCl.Cl.[H][C@@]12C(COC1=O)[C@H](CCN(C)CCCN(C)C)c1cc3OCOc3cc1[C@H]2c1cc(OC)c(O)c(OC)c1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: