| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM50024210 |
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| Substrate/Competitor | n/a |
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| Ki | 79.43±n/a nM |
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| Comments | PDSP_1920 |
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| Citation |  Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Cogé, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states. Synapse35:79-95 (2000) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT2C | HTR2C |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51631.71 |
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| Organism: | PORCINE |
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| Description: | K7GSR7 |
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| Residue: | 457 |
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| Sequence: | MVNLRKAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIILTIGGNILVIMAVSLEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISLGVSVPIPVIGLRDEDKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIHV
LRRQALMLLRGHTEEPPGISLDFLKCCKRNTDEENAANPNQDLNPRRRKKKERRPRGTMQ
AINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCS
GINPLVYTLFNKVYRRAFSNYLRCNYKADKKPPIRQIPRVAATALSGRELNVNIYRHTNE
PVIKKADDNEPGIEMQVENLELPVNPSNVVSERISSV
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| BDBM50024210 |
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| n/a |
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| Name | BDBM50024210 |
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| Synonyms: | 1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanamine | 2-(3-indolyl)ethylamine | CHEMBL6640 | tryptamine |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12N2 |
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| Mol. Mass. | 160.2157 |
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| SMILES | NCCc1c[nH]c2ccccc12 |
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| Structure | 
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