| Reaction Details |
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 | Report a problem with these data |
| Target | Anthranilate phosphoribosyltransferase |
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| Ligand | BDBM93077 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluoresence-based Assay |
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| Ki | 1.9e+4± 5e+3 nM |
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| Citation |  Castell, A; Short, FL; Evans, GL; Cookson, TV; Bulloch, EM; Joseph, DD; Lee, CE; Parker, EJ; Baker, EN; Lott, JS The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry52:1776-1787 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Anthranilate phosphoribosyltransferase |
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| Name: | Anthranilate phosphoribosyltransferase |
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| Synonyms: | Anthranilate phosphoribosyltransferase (Mtb-AnPRT) | TRPD_MYCTO | trpD |
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| Type: | Enzyme |
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| Mol. Mass.: | 37738.87 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WFX4 |
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| Residue: | 370 |
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| Sequence: | MALSAEGSSGGSRGGSPKAEAASVPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPA
QIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLST
MAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAP
RFHPSYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSS
VLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAA
VRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLL
ARWVRFGRQI
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| BDBM93077 |
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| n/a |
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| Name | BDBM93077 |
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| Synonyms: | ACS No 179 |
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| Type | Small molecule |
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| Emp. Form. | C17H10NO7 |
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| Mol. Mass. | 340.2643 |
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| SMILES | COc1cccc2c1cc([N+]([O-])=O)c1c(cc3OCOc3c21)C([O-])=O |
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| Structure | 
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